A Case-Control Study of the Association of the Polymorphisms and Haplotypes of DNA Ligase I with Lung and Upper-Aerodigestive-Tract Cancers

Tobacco smoking is a major risk factor for lung and upper-aerodigestive-tract (UADT) cancers. One possible mechanism for the associations may be through DNA damage pathways. DNA Ligase I (LIG1) is a DNA repair gene involved in both the nucleotide excision repair (NER) and base excision repair (BER)...

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Autors principals: Lee, Yuan-Chin Amy, Morgenstern, Hal, Greenland, Sander, Tashkin, Donald P., Papp, Jeanette, Sinsheimer, Janet, Cao, Wei, Hashibe, Mia, You, Nai-Chieh Y., Mao, Jenny T., Cozen, Wendy, Mack, Thomas M., Zhang, Zuo-Feng
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676936/
https://ncbi.nlm.nih.gov/pubmed/18059021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23274
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