Propentofylline attenuates allodynia, glial activation and modulates GABAergic tone after spinal cord injury in the rat

In this study, we evaluated whether propentofylline, a methylxanthine derivative, modulates spinal glial activation and GABAergic inhibitory tone by modulation of glutamic acid decarboxylase (GAD)(65), the GABA synthase enzyme, in the spinal dorsal horn following spinal cord injury (SCI). Sprague–Da...

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Hlavní autoři: Gwak, Young Seob, Crown, Eric D., Unabia, Geda C., Hulsebosch, Claire E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676790/
https://ncbi.nlm.nih.gov/pubmed/18353556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2008.01.021
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