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Propentofylline attenuates allodynia, glial activation and modulates GABAergic tone after spinal cord injury in the rat

In this study, we evaluated whether propentofylline, a methylxanthine derivative, modulates spinal glial activation and GABAergic inhibitory tone by modulation of glutamic acid decarboxylase (GAD)(65), the GABA synthase enzyme, in the spinal dorsal horn following spinal cord injury (SCI). Sprague–Da...

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Detalhes bibliográficos
Main Authors: Gwak, Young Seob, Crown, Eric D., Unabia, Geda C., Hulsebosch, Claire E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676790/
https://ncbi.nlm.nih.gov/pubmed/18353556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2008.01.021
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