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Pi-Pi complexation of bupivacaine and analogues with aromatic receptors: Implications for overdose remediation

The interaction of the important but often overdosed local anesthetic bupivacaine, its structural analogs 2,6-dimethylaniline, and N-methyl-2,6-dimethylacetanilide, and cocaine, with several electron deficient aromatic moieties were studied primarily by proton NMR and UV-visible spectroscopy. In sol...

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Main Authors: Powell, Evon, Lee, Y-H, Partch, Richard, Dennis, Donn, Morey, Timothy, Varshney, Manoj
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676660/
https://ncbi.nlm.nih.gov/pubmed/18019843
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