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Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: Current and developing technologies

The most common form of genetic variation, single nucleotide polymorphisms or SNPs, can affect the way an individual responds to the environment and modify disease risk. Although most of the millions of SNPs have little or no effect on gene regulation and protein activity, there are many circumstanc...

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Autori principali: Chorley, Brian N., Wang, Xuting, Campbell, Michelle R., Pittman, Gary S., Noureddine, Maher A., Bell, Douglas A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676583/
https://ncbi.nlm.nih.gov/pubmed/18565787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2008.05.001
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