Expression of Phospholipases A(2) in Primary Human Lung Macrophages. Role of Cytosolic Phospholipase A(2)–α in Arachidonic Acid Release and Platelet Activating Factor Synthesis

Macrophages are a major source of lipid mediators in the human lung. Expression and contribution of cytosolic (cPLA(2)) and secreted phospholipases A(2) (sPLA(2)) to the generation of lipid mediators in human macrophages is unclear. We investigated the expression and role of different PLA(2)s in the...

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Bibliografiska uppgifter
Huvudupphovsmän: Giannattasio, Giorgio, Lai, Ying, Granata, Francescopaolo, Mounier, Carine M., Nallan, Laxman, Oslund, Rob, Leslie, Christina C., Marone, Gianni, Lambeau, Gérard, Gelb, Michael H., Triggiani, Massimo
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676353/
https://ncbi.nlm.nih.gov/pubmed/19130898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2008.12.002
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