MTDH Activation by 8q22 Genomic Gain Promotes Chemoresistance and Metastasis of Poor-Prognosis Breast Cancer

Targeted therapy for metastatic diseases relies on the identification of functionally important metastasis genes from a large number of random genetic alterations. Here we use a computational algorithm to map minimal recurrent genomic alterations associated with poor-prognosis breast cancer. 8q22 ge...

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Hoofdauteurs: Hu, Guohong, Chong, Robert A., Yang, Qifeng, Wei, Yong, Blanco, Mario A., Li, Feng, Reiss, Michael, Au, Jessie L. –S., Haffty, Bruce G., Kang, Yibin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676231/
https://ncbi.nlm.nih.gov/pubmed/19111877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.11.013
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