Th-1 polarization is regulated by dendritic-cell comparison of MHC class I and class II antigens

In the control of T-helper type I (Th-1) polarization, dendritic cells (DCs) must interpret a complex array of stimuli, many of which are poorly understood. Here we demonstrate that Th-1 polarization is heavily influenced by DC-autonomous phenomena triggered by the loading of DCs with antigenically...

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Detalles Bibliográficos
Main Authors: Decker, William K., Xing, Dongxia, Li, Sufang, Robinson, Simon N., Yang, Hong, Steiner, David, Komanduri, Krishna V., Shpall, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2009
Assuntos:
Immunobiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676083/
https://ncbi.nlm.nih.gov/pubmed/19171878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-185470
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