Crystal Structures of YkuI and Its Complex with Second Messenger Cyclic Di-GMP Suggest Catalytic Mechanism of Phosphodiester Bond Cleavage by EAL Domains

Cyclic di-GMP (c-di-GMP) is a ubiquitous bacterial second messenger that is involved in the regulation of cell surface-associated traits and the persistence of infections. Omnipresent GGDEF and EAL domains, which occur in various combinations with regulatory domains, catalyze c-di-GMP synthesis and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Minasov, George, Padavattan, Sivaraman, Shuvalova, Ludmilla, Brunzelle, Joseph S., Miller, Darcie J., Baslé, Arnaud, Massa, Claudia, Collart, Frank R., Schirmer, Tilman, Anderson, Wayne F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Enzyme Catalysis and Regulation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676049/
https://ncbi.nlm.nih.gov/pubmed/19244251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808221200
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