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Generating an Unfoldase from Thioredoxin-like Domains

Protein-disulfide isomerase (PDI), an endoplasmic reticulum (ER)-resident protein, is primarily known as a catalyst of oxidative protein folding but also has a protein unfolding activity. We showed previously that PDI unfolds the cholera toxin A1 (CTA1) polypeptide to facilitate the ER-to-cytosol re...

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Detalhes bibliográficos
Main Authors: Forster, Michele L., Mahn, James J., Tsai, Billy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676037/
https://ncbi.nlm.nih.gov/pubmed/19289469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808352200
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