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Propagation of Tau Misfolding from the Outside to the Inside of a Cell
Tauopathies are neurodegenerative diseases characterized by aggregation of the microtubule-associated protein Tau in neurons and glia. Although Tau is normally considered an intracellular protein, Tau aggregates are observed in the extracellular space, and Tau peptide is readily detected in the cere...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2676015/ https://ncbi.nlm.nih.gov/pubmed/19282288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808759200 |
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