Darwinian and demographic forces affecting human protein coding genes

Past demographic changes can produce distortions in patterns of genetic variation that can mimic the appearance of natural selection unless the demographic effects are explicitly removed. Here we fit a detailed model of human demography that incorporates divergence, migration, admixture, and changes...

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Detalhes bibliográficos
Main Authors: Nielsen, Rasmus, Hubisz, Melissa J., Hellmann, Ines, Torgerson, Dara, Andrés, Aida M., Albrechtsen, Anders, Gutenkunst, Ryan, Adams, Mark D., Cargill, Michele, Boyko, Adam, Indap, Amit, Bustamante, Carlos D., Clark, Andrew G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675972/
https://ncbi.nlm.nih.gov/pubmed/19279335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.088336.108
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