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Interaction Between Cigarette Smoking and Clinical Benefit of Clopidogrel

OBJECTIVE: To examine the interaction between cigarette smoking and clinical efficacy of clopidogrel in STEMI. BACKGROUND: Cigarette smoking induces CYP1A2, which converts clopidogrel into its active metabolite, and prior studies suggest greater inhibition of platelet aggregation by clopidogrel in s...

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Detalhes bibliográficos
Main Authors: Desai, Nihar R., Mega, Jessica L., Jiang, Songtao, Cannon, Christopher P., Sabatine, Marc S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675920/
https://ncbi.nlm.nih.gov/pubmed/19358940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2008.12.044
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