Association of Megalin Genetic Polymorphisms with Prostate Cancer Risk and Prognosis

PURPOSE: Megalin, an endocytic receptor expressed by prostate epithelial cells, can internalize biologically active androgens bound to sex hormone binding globulin. Genetic variation within megalin could potentially influence levels of steroid hormone uptake. EXPERIMENTAL DESIGN: Forty haplotype-tag...

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Main Authors: Holt, Sarah K., Karyadi, Danielle M., Kwon, Erika M., Stanford, Janet L., Nelson, Peter S., Ostrander, Elaine A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675883/
https://ncbi.nlm.nih.gov/pubmed/18559602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4566
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