Serum Dickkopf-1 is increased and correlates with reduced bone mineral density in patients with thalassemia-induced osteoporosis. Reduction post-zoledronic acid administration

Dickkopf-1 is an inhibitor of Wnt signaling, which is crucial for osteoblast differentiation. We evaluated serum levels of Dickkopf-1 in 66 patients with thalassemia-induced osteoporosis who received therapy with zoledronic acid in a placebo-controlled, randomized trial. At baseline, thalassemia pat...

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Detalhes bibliográficos
Main Authors: Voskaridou, Ersi, Christoulas, Dimitrios, Xirakia, Charoula, Varvagiannis, Konstantinos, Boutsikas, Georgios, Bilalis, Antonios, Kastritis, Efstathios, Papatheodorou, Athanasios, Terpos, Evangelos
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2009
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675686/
https://ncbi.nlm.nih.gov/pubmed/19407319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haema-tol.2008.000893
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