In vitro hematopoietic and endothelial potential of flk-1(−/−) embryonic stem cells and embryos

Mice deficient in the Flk-1 receptor tyrosine kinase are known to die in utero because of defective vascular and hematopoietic development. Here, we show that flk-1(−/−) embryonic stem cells are nevertheless able to differentiate into hematopoietic and endothelial cells in vitro, although they give...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Schuh, Andre C., Faloon, Patrick, Hu, Qing-Long, Bhimani, Munsif, Choi, Kyunghee
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.2159
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