In vitro hematopoietic and endothelial potential of flk-1(−/−) embryonic stem cells and embryos

Mice deficient in the Flk-1 receptor tyrosine kinase are known to die in utero because of defective vascular and hematopoietic development. Here, we show that flk-1(−/−) embryonic stem cells are nevertheless able to differentiate into hematopoietic and endothelial cells in vitro, although they give...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Schuh, Andre C., Faloon, Patrick, Hu, Qing-Long, Bhimani, Munsif, Choi, Kyunghee
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1999
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.2159
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!