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CD26/dipeptidyl peptidase 4-deficiency alters thymic emigration patterns and leukcocyte subsets in F344-rats age-dependently

As CD26 (dipeptidyl peptidase 4/DPP4) rapidly truncates incretins N-terminally, including glucagon-like peptide-1, DPP4-inhibitors have been developed for treatment of diabetes type 2. To some extent this is surprising, as CD26/DPP4 is also deeply involved in immune regulation. Long-term pharmacolog...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Klemann, C, Schade, J, Pabst, R, Leitner, S, Stiller, J, von Hörsten, S, Stephan, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675268/
https://ncbi.nlm.nih.gov/pubmed/19055685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03839.x
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