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Identification of a nephritogenic immunodominant B and T cell epitope in experimental autoimmune glomerulonephritis

Experimental autoimmune glomerulonephritis (EAG) can be induced in Wistar Kyoto (WKY) rats by immunization with the non-collagenous domain (NC1) of the alpha 3 chain of type IV collagen, α3(IV)NC1. In patients with Goodpasture's disease, the major B cell epitope is located at the N-terminus of...

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Autors principals: Reynolds, J, Haxby, J, Juggapah, J K, Evans, D J, Pusey, C D
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675263/
https://ncbi.nlm.nih.gov/pubmed/19040602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03833.x
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