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Isolation and Characterization of Metalloproteases with a Novel Domain Structure by Construction and Screening of Metagenomic Libraries

Small-insert metagenomic libraries from four samples were constructed by a topoisomerase-based and a T4 DNA ligase-based approach. Direct comparison of both approaches revealed that application of the topoisomerase-based method resulted in a higher number of insert-containing clones per μg of enviro...

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Autori principali: Waschkowitz, Tanja, Rockstroh, Stephanie, Daniel, Rolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675231/
https://ncbi.nlm.nih.gov/pubmed/19218412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02136-08
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