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Huntingtin associated protein 1 and its functions

Huntington disease (HD) is caused by a polyglutamine expansion in the protein huntingtin (Htt). Several studies suggest that Htt and huntingtin associated protein 1 (HAP1) participate in intracellular trafficking and that polyglutamine expansion affects vesicular transport. Understanding the functio...

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Detalles Bibliográficos
Main Authors: Wu, Linda Lin-yan, Zhou, Xin-Fu
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675152/
https://ncbi.nlm.nih.gov/pubmed/19262167
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