In vitro and in vivo suppression of hepatocellular carcinoma growth by midkine-antisense oligonucleotide-loaded nanoparticles

AIM: To synthesize antisense oligonucleotides (ASODNs) of midkine (MK), package the ASODNs with nanoparticles, and to inhibit hepatocellular carcinoma (HCC) growth using these nanoparticles. METHODS: HepG2 cell proliferation was analyzed in vitro using the 3-(4,5-dimethythiazol-2-yl)-5-(3-carboxymet...

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Bibliografiska uppgifter
Huvudupphovsmän: Dai, Li-Cheng, Yao, Xing, Wang, Xiang, Niu, Shu-Qiong, Zhou, Lin-Fu, Fu, Fang-Fang, Yang, Shui-Xin, Ping, Jin-Liang
Materialtyp: Artigo
Språk:Inglês
Publicerad: The WJG Press and Baishideng 2009
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Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675086/
https://ncbi.nlm.nih.gov/pubmed/19399928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.15.1966
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