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Screening a genome wide S. pombe deletion library identifies novel genes and pathways involved in the DNA damage response

The maintenance of genome stability is essential for an organism to avoid cell death and cancer. Based on screens for mutant sensitivity against DNA damaging agents a large number of DNA repair and DNA damage checkpoint genes have previously been identified in genetically amenable model organisms. T...

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Detalhes bibliográficos
Main Authors: Deshpande, Gaurang P., Hayles, Jacqueline, Hoe, Kwang-Lae, Kim, Dong-Uk, Park, Han-Oh, Hartsuiker, Edgar
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675035/
https://ncbi.nlm.nih.gov/pubmed/19264558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.01.016
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