Interleukin-17–producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers

OBJECTIVE: To identify interleukin-17 (IL-17)–producing T cells from patients with juvenile idiopathic arthritis (JIA), and investigate their cytokine production, migratory capacity, and relationship to Treg cells at sites of inflammation, as well as to test the hypothesis that IL-17+ T cell numbers...

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Main Authors: Nistala, Kiran, Moncrieffe, Halima, Newton, Katy R, Varsani, Hemlata, Hunter, Patricia, Wedderburn, Lucy R
Formato: Artigo
Idioma:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2008
Assuntos:
Childhood Arthritis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675006/
https://ncbi.nlm.nih.gov/pubmed/18311821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23291
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