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The Evolution of Epistasis and Its Links With Genetic Robustness, Complexity and Drift in a Phenotypic Model of Adaptation
The epistatic interactions among mutations have a large effect on the evolution of populations. In this article we provide a formalism under which epistatic interactions among pairs of mutations have a distribution whose mean can be modulated. We find that the mean epistasis is correlated to the eff...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Genetics Society of America
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674823/ https://ncbi.nlm.nih.gov/pubmed/19279327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.099127 |
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