Identification of EMS-Induced Mutations in Drosophila melanogaster by Whole-Genome Sequencing

Next-generation methods for rapid whole-genome sequencing enable the identification of single-base-pair mutations in Drosophila by comparing a chromosome bearing a new mutation to the unmutagenized sequence. To validate this approach, we sought to identify the molecular lesion responsible for a rece...

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Main Authors: Blumenstiel, Justin P., Noll, Aaron C., Griffiths, Jennifer A., Perera, Anoja G., Walton, Kendra N., Gilliland, William D., Hawley, R. Scott, Staehling-Hampton, Karen
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2009
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Investigations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674820/
https://ncbi.nlm.nih.gov/pubmed/19307605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.101998
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