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Analysis of the Sequence and Phenotype of Drosophila Sex combs reduced Alleles Reveals Potential Functions of Conserved Protein Motifs of the Sex combs reduced Protein

The Drosophila Hox gene, Sex combs reduced (Scr), is required for patterning the larval and adult, labial and prothoracic segments. Fifteen Scr alleles were sequenced and the phenotypes analyzed in detail. Six null alleles were nonsense mutations (Scr(2), Scr(4), Scr(11), Scr(13), Scr(13A), and Scr(...

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Autori principali: Sivanantharajah, Lovesha, Percival-Smith, Anthony
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674816/
https://ncbi.nlm.nih.gov/pubmed/19293143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.100438
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