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Association of the Complement Factor H Y402H Polymorphism With Cardiovascular Disease Is Dependent Upon Hypertension Status: The ARIC Study

BACKGROUND: Complement factor H (CFH) is a plasma protein that is essential in the regulation of the alternative complement pathway and has been implicated as taking part in complement inhibition in atherogenesis. We evaluated the association of the y402H polymorphism with incident coronary heart di...

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Detalhes bibliográficos
Main Authors: Volcik, Kelly A., Ballantyne, Christie M., Braun, Michael C., Coresh, Josef, Mosley, Thomas H., Boerwinkle, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674647/
https://ncbi.nlm.nih.gov/pubmed/18292760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajh.2007.81
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