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TNF induction of jagged-1 in endothelial cells is NFκB-dependent
TNF-α is a potent proinflammatory cytokine that induces endothelial cell (EC) adhesion molecules. In addition, TNF promotes angiogenesis by inducing an EC tip cell phenotype and the expression of jagged-1, a ligand for the notch pathway. Notch signaling is critical for vascular patterning and helps...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674625/ https://ncbi.nlm.nih.gov/pubmed/19393188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2009.01.003 |
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