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Developmental Regulation of Hepatitis B Virus Biosynthesis by Hepatocyte Nuclear Factor 4α

The host cellular factors that promote persistent viral infections in vivo are, in general, poorly understood. Utilizing the hepatitis B virus (HBV) transgenic mouse model of chronic infection, we demonstrate that the nuclear receptor, hepatocyte nuclear factor 4α (HNF4α, NR2A1), is essential for vi...

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Detalhes bibliográficos
Main Authors: Li, Lie, Oropeza, Claudia E., Sainz, Bruno, Uprichard, Susan L., Gonzalez, Frank J., McLachlan, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674568/
https://ncbi.nlm.nih.gov/pubmed/19424486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005489
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