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Total Synthesis of Sporolide B

[Image: see text] The first total synthesis of the highly oxygenated, marine derived, natural product sporolide B was achieved through a convergent strategy involving a ruthenium-catalyzed [2+2+2] cycloaddition to assemble the indene structural motif and a thermally-induced Diels-Alder-type reaction...

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Detalhes bibliográficos
Main Authors: Nicolaou, K. C., Tang, Yefeng, Wang, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674522/
https://ncbi.nlm.nih.gov/pubmed/19241430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200900264
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