Mefloquine pharmacokinetics and mefloquine-artesunate effectiveness in Peruvian patients with uncomplicated Plasmodium falciparum malaria

BACKGROUND: Artemisinin-based combination therapy (ACT) is recommended as a means of prolonging the effectiveness of first-line malaria treatment regimens. Different brands of mefloquine (MQ) have been reported to be non-bioequivalent; this could result in sub-therapeutic levels of mefloquine with d...

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Main Authors: Gutman, Julie, Green, Michael, Durand, Salomon, Rojas, Ofelia Villalva, Ganguly, Babita, Quezada, Wilmer Marquiño, Utz, Gregory C, Slutsker, Laurence, Ruebush, Trenton K, Bacon, David J
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674465/
https://ncbi.nlm.nih.gov/pubmed/19358697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-8-58
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