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The evolution of Runx genes II. The C-terminal Groucho recruitment motif is present in both eumetazoans and homoscleromorphs but absent in a haplosclerid demosponge

BACKGROUND: The Runt DNA binding domain (Runx) defines a metazoan family of sequence-specific transcription factors with essential roles in animal ontogeny and stem cell based development. Depending on cis-regulatory context, Runx proteins mediate either transcriptional activation or repression. In...

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Detalhes bibliográficos
Main Authors: Robertson, Anthony J, Larroux, Claire, Degnan, Bernard M, Coffman, James A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674455/
https://ncbi.nlm.nih.gov/pubmed/19374764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-2-59
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