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Human oligodendrocytes from embryonic stem cells: conserved SHH signaling networks and divergent FGF effects
Human embryonic stem cells (hESCs) offer a platform to bridge what we have learned from animal studies to human biology. Using oligodendrocyte differentiation as a model system, we show that sonic hedgehog (SHH)-dependent sequential activation of the transcription factors OLIG2, NKX2.2 and SOX10 is...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674255/ https://ncbi.nlm.nih.gov/pubmed/19363151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.029447 |
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