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Focal Reduction of αE-catenin Causes Premature Differentiation and Reduction of β-catenin Signaling During Cortical Development
Cerebral cortical precursor cells reside in a neuroepithelial cell layer that regulates their proliferation and differentiation. Global disruptions in epithelial architecture induced by loss of the adherens junction component αE-catenin lead to hyperproliferation. Here we show that cell autonomous r...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674140/ https://ncbi.nlm.nih.gov/pubmed/19389371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.01.010 |
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