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Focal Reduction of αE-catenin Causes Premature Differentiation and Reduction of β-catenin Signaling During Cortical Development

Cerebral cortical precursor cells reside in a neuroepithelial cell layer that regulates their proliferation and differentiation. Global disruptions in epithelial architecture induced by loss of the adherens junction component αE-catenin lead to hyperproliferation. Here we show that cell autonomous r...

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Detalles Bibliográficos
Main Authors: Stocker, Adam M., Chenn, Anjen
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674140/
https://ncbi.nlm.nih.gov/pubmed/19389371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.01.010
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