Natural genetic variation in transcriptome reflects network structure inferred with major effect mutations: insulin/TOR and associated phenotypes in Drosophila melanogaster

BACKGROUND: A molecular process based genotype-to-phenotype map will ultimately enable us to predict how genetic variation among individuals results in phenotypic alterations. Building such a map is, however, far from straightforward. It requires understanding how molecular variation re-shapes devel...

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Hlavní autoři: Nuzhdin, Sergey V, Brisson, Jennifer A, Pickering, Andrew, Wayne, Marta L, Harshman, Lawrence G, McIntyre, Lauren M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674066/
https://ncbi.nlm.nih.gov/pubmed/19317915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-124
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