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Activation of the Hedgehog Pathway in the Mouse Fetal Ovary Leads to Ectopic Appearance of Fetal Leydig Cells and Female Pseudohermaphroditism
Proper cell fate determination in mammalian gonads is critical for the establishment of sexual identity. The Hedgehog (Hh) pathway has been implicated in cell fate decision for various organs, including gonads. Desert Hedgehog (Dhh), one of the three mammalian Hh genes, has been implicated with othe...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673990/ https://ncbi.nlm.nih.gov/pubmed/19268447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.02.025 |
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