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Glutaric acid as a spacer facilitates improved intracellular uptake of LHRH–SPION into human breast cancer cells

Superparamagnetic iron oxide nanoparticles (SPIONs) bound directly to luteinizing hormone releasing hormone (LHRH) have shown high efficiency for intracellular uptake to breast cancer cells, MDA-MB-435S.luc. We demonstrate in this communication that inclusion of a small spacer molecule such as gluta...

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Detalhes bibliográficos
Main Authors: Kumar, Challa SSR, Leuschner, Carola, Urbina, Michelle, Ozkaya, Tevhida, Hormes, Josef
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673973/
https://ncbi.nlm.nih.gov/pubmed/17722545
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