Ablation of a Ca(2+)-activated K(+) channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation

Small conductance Ca(2+)-activated K(+) channels (SK channels) have been reported in excitable cells, where they aid in integrating changes in intracellular Ca(2+)[Image: see text] with membrane potential. We have recently reported the functional existence of SK2 channels in human and mouse cardiac...

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Hlavní autoři: Li, Ning, Timofeyev, Valeriy, Tuteja, Dipika, Xu, Danyan, Lu, Ling, Zhang, Qian, Zhang, Zhao, Singapuri, Anil, Albert, Trevine R, Rajagopal, Amutha V, Bond, Chris T, Periasamy, Muthu, Adelman, John, Chiamvimonvat, Nipavan
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2009
Témata:
Cardiovascular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673777/
https://ncbi.nlm.nih.gov/pubmed/19139040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.167718
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