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Constitutive expression of Bcl-2 in the haematopoietic compartment alters the metabolism of iron and increases resistance to mycobacterial infection

Mice expressing a vav-bcl-2 transgene were tested for their resistance to an experimental infection with Mycobacterium avium. When compared with control littermates, transgenic mice exhibited an increase in the resistance to infection which was independent of B or T lymphocytes and did not require t...

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Autors principals: Flórido, M, Borges, M, Rodrigues, P, Vale-Costa, S, Gomes, M Salomé, Appelberg, R
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673742/
https://ncbi.nlm.nih.gov/pubmed/19210523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03867.x
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