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Highly sensitive and quantitative FRET-FLIM imaging in single dendritic spines using improved non-radiative YFP

Two-photon fluorescence lifetime imaging microscopy (TPFLIM) enables the quantitative measurements of fluorescence resonance energy transfer (FRET) in small subcellular compartments in light scattering tissue. We evaluated and optimized the FRET pair of mEGFP (monomeric EGFP with the A206K mutation)...

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Detalhes bibliográficos
Main Authors: Murakoshi, Hideji, Lee, Seok-Jin, Yasuda, Ryohei
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673728/
https://ncbi.nlm.nih.gov/pubmed/18512154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11068-008-9024-9
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