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Genomic analysis of COP9 signalosome function in Drosophila melanogaster reveals a role in temporal regulation of gene expression

The COP9 signalosome (CSN), an eight-subunit protein complex, is conserved in all higher eukaryotes. CSN intersects the ubiquitin–proteasome pathway, modulating signaling pathways controlling various aspects of development. We are using Drosophila as a model system to elucidate the function of this...

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Detalhes bibliográficos
Main Authors: Oron, Efrat, Tuller, Tamir, Li, Ling, Rozovsky, Nina, Yekutieli, Daniel, Rencus-Lazar, Sigal, Segal, Daniel, Chor, Benny, Edgar, Bruce A, Chamovitz, Daniel A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673709/
https://ncbi.nlm.nih.gov/pubmed/17486136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100150
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