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Myc Prevents Apoptosis and Enhances Endoreduplication Induced by Paclitaxel

BACKGROUND: The role of the MYC oncogene in the apoptotic pathways is not fully understood. MYC has been reported to protect cells from apoptosis activation but also to sensitize cells to apoptotic stimuli. We have previously demonstrated that the down-regulation of Myc protein activates apoptosis i...

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Detalhes bibliográficos
Principais autores: Gatti, Giuliana, Maresca, Giovanna, Natoli, Manuela, Florenzano, Fulvio, Nicolin, Angelo, Felsani, Armando, D'Agnano, Igea
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673584/
https://ncbi.nlm.nih.gov/pubmed/19421315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005442
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