Novel celiac disease genetic determinants related to the immune response

Our celiac disease genome-wide association study identified IL2/IL21 region risk variants. We genotyped 1,020 of the most associated non-HLA markers in a further 1,643 cases and 3,406 controls. Joint analysis including the genome-wide association study data (767 cases, 1422 controls) identified seve...

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Autors principals: Hunt, Karen A, Zhernakova, Alexandra, Turner, Graham, Heap, Graham A.R., Franke, Lude, Bruinenberg, Marcel, Romanos, Jihane, Dinesen, Lotte C., Ryan, Anthony W, Panesar, Davinder, Gwilliam, Rhian, Takeuchi, Fumihiko, McLaren, William M, Holmes, Geoffrey KT, Howdle, Peter D, Walters, Julian RF, Sanders, David S, Playford, Raymond J, Trynka, Gosia, Mulder, Chris JJ, Mearin, M Luisa, Verbeek, Wieke HM, Trimble, Valerie, Stevens, Fiona M, O’Morain, Colm, Kennedy, Nicholas P, Kelleher, Dermot, Pennington, Daniel J, Strachan, David P, McArdle, Wendy L, Mein, Charles A, Wapenaar, Martin C, Deloukas, Panos, McGinnis, Ralph, McManus, Ross, Wijmenga, Cisca, van Heel, David A
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673512/
https://ncbi.nlm.nih.gov/pubmed/18311140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.102
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