CHOLINESTERASE INHIBITION AND ACETYLCHOLINE ACCUMULATION FOLLOWING INTRACEREBRAL ADMINISTRATION OF PARAOXON IN RATS

We evaluated the inhibition of striatal cholinesterase activity following intracerebral administration of paraoxon assaying activity either in tissue homogenates ex vivo or by substrate hydrolysis in situ. Artificial cerebrospinal fluid (aCSF) or paraoxon in aCSF was infused unilaterally (0.5 μl/min...

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Detalhes bibliográficos
Main Authors: Ray, A., Liu, J., Karanth, S., Gao, Y., Brimijoin, S., Pope, C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673459/
https://ncbi.nlm.nih.gov/pubmed/19272400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2009.02.022
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