Genetic changes of p53, K-ras, and microsatellite instability in gallbladder carcinoma in high-incidence areas of Japan and Hungary

AIM: To disclose geographic differences in genetic changes involved in gallbladder carcinogenesis between two distinct high-incidence areas of Japan and Hungary. METHODS: We examined 42 cases of gallbladder carcinoma: 22 Japanese and 20 Hungarian cases. p53 mutations at exons 5 to 8 and K-ras mutati...

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Autores principales: Nagahashi, Masayuki, Ajioka, Yoichi, Lang, Istvan, Szentirmay, Zoltan, Kasler, Miklos, Nakadaira, Hiroto, Yokoyama, Naoyuki, Watanabe, Gen, Nishikura, Ken, Wakai, Toshifumi, Shirai, Yoshio, Hatakeyama, Katsuyoshi, Yamamoto, Masaharu
Formato: Artigo
Lenguaje:Inglês
Publicado: The WJG Press and Baishideng 2008
Materias:
Rapid Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673394/
https://ncbi.nlm.nih.gov/pubmed/18176964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.70
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