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A simple reference state makes a significant improvement in near-native selections from structurally refined docking decoys

Near-native selections from docking decoys have proved challenging especially when unbound proteins are used in the molecular docking. One reason is that significant atomic clashes in docking decoys lead to poor predictions of binding affinities of near native decoys. Atomic clashes can be removed b...

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Détails bibliographiques
Auteurs principaux: Liang, Shide, Liu, Song, Zhang, Chi, Zhou, Yaoqi
Format: Artigo
Langue:Inglês
Publié: Wiley Subscription Services, Inc., A Wiley Company 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673351/
https://ncbi.nlm.nih.gov/pubmed/17623864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21498
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