Dynamin-dependent Membrane Drift Recruits AMPA Receptors to Dendritic Spines

The surface expression and localization of AMPA receptors (AMPARs) at dendritic spines are tightly controlled to regulate synaptic transmission. Here we show that de novo exocytosis of the GluR2 AMPAR subunit occurs at the dendritic shaft and that new AMPARs diffuse into spines by lateral diffusion...

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Bibliographic Details
Main Authors: Jaskolski, Frédéric, Mayo-Martin, Belen, Jane, David, Henley, Jeremy M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673315/
https://ncbi.nlm.nih.gov/pubmed/19269965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808401200
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