Structure of the Tyrosine-sulfated C5a Receptor N Terminus in Complex with Chemotaxis Inhibitory Protein of Staphylococcus aureus

Complement component C5a is a potent pro-inflammatory agent inducing chemotaxis of leukocytes toward sites of infection and injury. C5a mediates its effects via its G protein-coupled C5a receptor (C5aR). Although under normal conditions highly beneficial, excessive levels of C5a can be deleterious t...

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Main Authors: Ippel, Johannes H., de Haas, Carla J. C., Bunschoten, Anton, van Strijp, Jos A. G., Kruijtzer, John A. W., Liskamp, Rob M. J., Kemmink, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673304/
https://ncbi.nlm.nih.gov/pubmed/19251703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808179200
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