Metallic nickel nano- and fine particles induce JB6 cell apoptosis through a caspase-8/AIF mediated cytochrome c-independent pathway

BACKGROUND: Carcinogenicity of nickel compounds has been well documented. However, the carcinogenic effect of metallic nickel is still unclear. The present study investigates metallic nickel nano- and fine particle-induced apoptosis and the signal pathways involved in this process in JB6 cells. The...

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Autori principali: Zhao, Jinshun, Bowman, Linda, Zhang, Xingdong, Shi, Xianglin, Jiang, Binghua, Castranova, Vincent, Ding, Min
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673202/
https://ncbi.nlm.nih.gov/pubmed/19379505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3155-7-2
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