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Establishment of Intestinal Identity and Epithelial-Mesenchymal Signaling by Cdx2

We demonstrate that conditional ablation of the homeobox transcription factor Cdx2 from early endoderm results in the replacement of the posterior intestinal epithelium with keratinocytes, a dramatic cell fate conversion caused by ectopic activation of the foregut/esophageal differentiation program....

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Bibliografiske detaljer
Main Authors: Gao, Nan, White, Peter, Kaestner, Klaus H.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673200/
https://ncbi.nlm.nih.gov/pubmed/19386267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.02.010
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