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Microglia enhance manganese chloride-induced dopaminergic neurodegeneration: role of free radical generation

Exposure to elevated levels of manganese has been shown to cause neuronal damage in the midbrain and the development of Parkinsonian symptoms. Activation of microglia and release of neurotoxic factors in particular free radicals are known to contribute to neurodegeneration. We have recently reported...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Ping, Wong, Tamika A., Lokuta, Kyle M., Turner, DeAnne E., Vujisic, Kristina, Liu, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673144/
https://ncbi.nlm.nih.gov/pubmed/19268665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.02.013
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